P3.02c-023 Mutation and Prognostic Analyses of PIK3CA in Patients with Completely Resected Lung Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Mutation and prognostic analyses of PIK3CA in patients with completely resected lung adenocarcinoma
PIK3CA mutation represents a clinical subset of diverse carcinomas. We explored the status of PIK3CA mutation and evaluated its genetic variability, treatment, and prognosis in patients with lung adenocarcinoma. A total of 810 patients with completely resected lung adenocarcinoma were recruited between 2008 and 2013. The status of PIK3CA mutation and other three genes, that is, EGFR mutation, K...
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PURPOSE PIK3CA gene mutations have been detected in many malignancies, but the frequency of different mutations and their role in the carcinogenesis of lung adenocarcinoma are still unclear. The purpose of this study was to explore the clinical pathological impact and prognostic implications of PIK3CA mutations in lung adenocarcinoma. METHODS Five common PIK3CA mutations (E542K, E545K, and E5...
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BACKGROUND Treatment strategies for brain metastasis from lung cancer have been making progress. The aim of this retrospective analysis was to investigate the post-recurrent prognostic factors in patients with brain metastasis after complete resection of non-small cell lung cancer (NSCLC). METHODS We retrospectively reviewed the medical records of 40 patients found to have postoperative brain...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2016.11.1818